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内容简介:
Part of the prestigious Novartis Foundation series, this volume uniquely addresses the use of innate immunity to treat or prevent infectious diseases of the lung.
Innate Immunity to Pulmonary Infection:
Provides a comprehensive overview of pulmonary infectious diseases, including basic pathology, current and potential therapies, and detailed consideration of the innate biological resistance mechanisms in the lung
Thoroughly examines the major topic of innate immunity in immunology, which is now seen as key to the pathogenesis of and vaccination strategies for infectious diseases
Describes the genetic and environmental factors which determine the outcome of infection, such as latency of Tuberculosis, blood stream invasion from local infection, and local target tissue damage
Covers the roles of cells such as neutrophils, macrophages and dendritic cells and of molecular components such as Toll-like receptors
Discusses the clinical applications of the new knowledge regarding innate immunity and how this can be used in both treatment and prevention ?(vaccination) strategies
Includes contributions from an international and interdisciplinary group of experts
Innate Immunity to Pulmonary Infection is an essential resource for researchers in both industry and academia. It is of interest for all those interested in the disciplines of immunology, virology, biology, biotechnology and genetics.
书籍目录:
Symposium on Innate immunity to pulmonary infection, held at the Wolfson Pavillion,University of Cape Town Medical School, South Africa, 28-30 November 2005
Editors: Derek J. Chadwick (Organizer) and]amie Goode
This symposium is based on a proposal made by Siamon Gordon and Gordon Brown
Siamon Gordon Chair's introduction
Eric D. Bateman and Anamika Jithoo Lung diseases in South Africa: an
overview
Discussion
Paul D. van Helden, Marlo Mo11er, Chantal Babb, Robin Warren, Gerhard Walzl, Pieter Uys and Eileen Hoal TB epidemiology and human
genetics
Discussion
David P. Speert Bacterial infections of the lung in normal and immunodeficient patients
Discussion
Malik Peiris Pathogenesis of avian flu H5N1 and SARS
Discussion
Claudia Montagnoli, Silvia Bozza, Roberta Gaziano, Teresa Zelante, Pierluigi Bonifazi, Silvia Moretti, Silvia Bellocchio, Lucia Pitzurra and Luigina Romani Immunity and tolerance to Aspergillusfumigatus
Discussion
Cecilia Garlanda, Barbara Bottazzi, Giovanni Salvatori, Rita De Santis,Alessia Cotena, Livija Deban, Viriginia Maina, Federica Moalli, Andrea Doni, Tania Veliz-Rodriguez and Alberto Mantovani Pentraxins in innate immunity and inflammation
Discussion
Anthony W. Segal How superoxide production by neutrophil leukocytes kills microbes
Discussion
Ralph M. Steinman Linking innate to adaptive immunity through dendritic cells
Discussion
Gordon D. Brown Macrophage receptors and innate immunity: insights from dectin-1
Discussion
Bernhard Ryffel, Muazzam Jacobs, Shreemanta Parida, Tania Botha,Dieudonnee Togbe and Valerie Quesniaux Toll-like receptors and control of mycobacterial infection in mice
Discussion
T. J. Williams and C. t. Weller Population of lungs by mast cells
Discussion
John K. Sheehan, Mehmet Kesimer and Raymond Pickles Innate immunity and mucus structure and function
Discussion
R. B. Sire, H. Clark, K. Hajela and K. R. Mayilyan Collectins and host defence
Discussion
Bart N. Lambrecht and Leonie S. van Rijt Infections and asthma pathogenesis: a critical role for dendritic cells?
Discussion
t. A. Vella and O. J. Finn Innate and adaptive immunity in lung cancer
Discussion
Siamon Gordon Summing-up
Index of contributors
Subject index
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作者简介
The Novartis Foundation is an international scientific and educational charity which promotes the study and general knowledge of science and in particular encourages international co-operation in scientific research.
书籍介绍
Part of the prestigious Novartis Foundation series, this volume uniquely addresses the use of innate immunity to treat or prevent infectious diseases of the lung. Innate Immunity to Pulmonary Infection: Provides a comprehensive overview of pulmonary infectious diseases, including basic pathology, current and potential therapies, and detailed consideration of the innate biological resistance mechanisms in the lung Thoroughly examines the major topic of innate immunity in immunology, which is now seen as key to the pathogenesis of and vaccination strategies for infectious diseases Describes the genetic and environmental factors which determine the outcome of infection, such as latency of Tuberculosis, blood stream invasion from local infection, and local target tissue damage Covers the roles of cells such as neutrophils, macrophages and dendritic cells and of molecular components such as Toll-like receptors Discusses the clinical applications of the new knowledge regarding innate immunity and how this can be used in both treatment and prevention (vaccination) strategies Includes contributions from an international and interdisciplinary group of experts Innate Immunity to Pulmonary Infection is an essential resource for researchers in both industry and academia. It is of interest for all those interested in the disciplines of immunology, virology, biology, biotechnology and genetics.
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